In attempts to understand better the regions of the brain that are linked to Alzheimer’s disease, the US scientists have made what they believe to be the most detailed map of the brain’s memory area – the hippocampus.
The map which was made using 3D animation and fluorescent tracers displays the structures, nerve connections, and functions of the hippocampus with much detail.
The lead author of the study, Michael Bienkowski from the Keck School of Medicine of the University of Southern California said:
Like a new atlas, we’ve constructed the most detailed diagram of the hippocampus to date.
With a better map, we can see each region and how it functions. A better map is a resource scientist can use to better understand the hippocampus and how its degeneration leads to diseases.
For those of you who are not aware of the human hippocampus, it is the part of the brain which is situated at the bottom and is structured like a seahorse. It takes care of storing memories, guides navigation by spatial processing and helps to control emotions.
With this latest map, the scientists can discuss more the sub-regions and how the cells interact across the structure.
It totally changes our understanding by combining a wiring diagram with the gene expression of the mouse hippocampus. We see it doing different things, and this gives us a new way to understand how the whole thing works together. This should have a very profound and broad impact.
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